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Cholestrol Modulation of Protein Function: Sterol Specificity and Indirect Mechanisms

Rosenhouse-D
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Book Information
Edition: 1st
Publisher: Springer Nature
ISBN: 3-030-04278-2 (3030042782)
ISBN-13: 978-3-030-04278-3 (9783030042783)
Binding: E E Book + ProQuest Ebook Central
Copyright: 2019
Publish Date: 02/19
Volume: 1115
Weight: 0.00 Lbs.
Subject Class: BIO (Biostatistics and Epidemiology)
Return Policy: Non-Returnable.
   
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Class Specifications
ISSN Series: Advances in Experimental Medicine & Biology
Discipline: Biochemistry
Subject Definition: Cholesterol
NLM Class: QU 95
LC Class: QP752
Abstract: In this book, renowned scientists describe the role of steroid chirality and modification of lipid membrane physical properties in the modulation of G protein-coupled receptors and ion channels. The application of commonly-used technical approaches such as mass spectrometry and nucleic magnetic resonance transfer spectroscopy for studies on cholesterol distribution and alteration of lipid bilayer characteristics is also discussed. This book offers comprehensive insights into the current understanding of cholesterol-driven modulation of protein function via mechanisms that extend beyond lipid-protein direct interactions. In the first part, the chapters introduce the reader to the use of the chemical derivatives of cholesterol as a valuable laboratory tool in the studies of cholesterol-driven modulation of protein function.
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