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Polymyxin Antibiotics: From Laboratory Bench to Bedside

Li, Jian

Polymyxin Antibiotics: From Laboratory Bench to Bedside Cover Image

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Book Information
Edition:	1st
Publisher:	Springer Nature
ISBN:	3-030-16371-7 (3030163717)
ISBN-13:	978-3-030-16371-6 (9783030163716)
Binding:	Hardcover
Copyright:	2019
Publish Date:	05/19
Volume:	1145
Weight:	1.88 Lbs.
Pages:	365
Subject Class:	BIO (Biostatistics and Epidemiology)
Return Policy:	Returns accepted up to 12 months provided no other recalls or return restrictions apply.
Contributing Authors:	View
ProQuest Ebook Central:	Available in ProQuest Ebook Central™ View

Class Specifications
ISSN Series:	Advances in Experimental Medicine & Biology
Discipline:	Pharmacology
Subject Definition:	Polymyxins; Anti-Bacterial Agents
NLM Class:	QV 350
LC Class:	RM267
Abstract:	This volume is the first-ever complete treatise on polymyxins and presents the most comprehensive and up-to-date reviews of all major research and clinical topics from chemistry, microbiology, pharmacology, clinical use, to drug discovery. All chapters were written by internationally leading researchers and clinicians in the field. It is our wish that readers discover the importance of polymyxin structure in relation to the mechanisms of activity, resistance and toxicity. We emphasized that reliable analytic methods for polymyxins are critical when investigating their pharmacokinetics (PK) and pharmacodynamics (PD). The complicated dose definitions and different pharmacopoeial standards have already compromised the safe use of polymyxins in patients. Therefore, informed by the latest pharmacological information, scientifically-based dosing recommendations have been proposed for intravenous polymyxins.

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