Allosteric Modulation for Drug Discovery

Zhong, Huailing

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Book Information
Edition:	1st
Publisher:	Wiley, John & Sons, Inc.
ISBN:	1-118-56857-5 (1118568575)
ISBN-13:	978-1-118-56857-6 (9781118568576)
Binding:	Hardcover
Copyright:	2018
Weight:	0.00 Lbs.
Pages:	608
Subject Class:	PRM (Pharmacology)
Remarks:	This Publication Has Been Cancelled
Return Policy:	Returns accepted up to 12 months provided no other recalls or return restrictions apply.

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Abstract:

A bridge for industrial and academic collaborations, this book overviews the concepts and therapeutic application of allosteric modulation to control protein function explaining why it has gained strong momentum in drug discovery, technologies and methodologies to discover allosteric modulators, and allosteric modulator compounds. Collects into one single resource the details on allosteric modulation of key drug targets, making for an encyclopedic coverage from basics to drug discovery applications Describes methods to detect and analyze allosterism Lets readers compare how allosteric modulators function and used across different platforms Includes the major drug target classes with demonstrated allosteric modulation Features a companion website with color images and protocols that readers can access

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