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Product Detail
Inflammasomes: Clinical and Therpeutic Implications
Cordero, Mario D.
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List Price:$179.99
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Other formats:
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Book Information
Edition:
1st
Publisher:
Springer Nature
ISBN:
3-319-89389-0 (3319893890)
ISBN-13:
978-3-319-89389-1 (9783319893891)
Binding:
Hardcover
Copyright:
2018
Publish Date:
01/18
Volume:
108
Weight:
1.63 Lbs.
Pages:
400
Subject Class:
PUB (Public Health)
Return Policy:
Returns accepted up to 12 months provided no other recalls or return restrictions apply.
Contributing Authors:
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ProQuest Ebook Central:
Available in ProQuest Ebook Central™
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Class Specifications
ISSN Series:
Experientia Supplementum
Discipline:
Pathology
Subject Definition:
Inflammation
NLM Class:
QZ 150
LC Class:
RB131
Abstract:
The inflammasome is a protein complex composed of an intracellular sensor typically a Nod like receptor, the precursor procaspase 1, and the adaptor ASC. Inflammasome activation leads to the maturation of caspase 1 and the processing of its substrates, IL 1 and IL 18. There is a need for reestablishing the real benefits of the inflammasome inhibitions in pathological situations and the management of the differents diseases where inflammasomes are implicated. ...This project will show the context where inflammasomes are being studied and the molecular implications in the medical and clinical contexts. ...Other important topic of the inflammasomes will be the development of pharmacological inhibitors in order to improve new clinical applications. In this sense, we can find new drugs with inhibitory effects or old drugs with an inhibitory potential effect.
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