Distributing since 1889 • Employee Owned for Better Service

Your 1st Choice!

Quick Search:

Cart | My Account | View Printable Page

Product Detail

NOTICE: This is the ProQuest Ebook Centralï¿½ format of this title. What is ProQuest Ebook Centralï¿½?

Other formats:

Hardcover

All Formats

ABC Transporters and Multidrug Resistance

Boumendjel, Ahcene

Pricing & Availability
Available: Yes*
This title does not qualify for any discount.

Email this title to a friend

Printer friendly version

Other formats:

Book Information
Edition:	1st
Publisher:	Wiley, John & Sons, Inc.
ISBN:	0-470-49512-X (047049512X)
ISBN-13:	978-0-470-49512-4 (9780470495124)
Binding:	E E Book + ProQuest Ebook Central
Copyright:	2009
Publish Date:	07/09
Weight:	0.00 Lbs.
Carton Quantity:	18
Subject Class:	PRM (Pharmacology)
Return Policy:	Non-Returnable.
Table Of Contents:	View

ProQuest Ebook Centralï¿½:	Please sign in to preview this title

Class Specifications
ISSN Series:	Wiley Series in Drug Discovery and Development
Discipline:	Biochemistry
Subject Definition:	Multidrug Resistance-Associated Proteins
NLM Class:	QU 55.7
LC Class:	QP552
Abstract:	A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance. ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to target and destroy such cells. In MDR, patients who are on medication eventually develop resistance to not only the drug they are taking, but to several different types of drugs. ABC Transporters and Multidrug Resistance offers an essential resource for pharmaceutical researchers who are working to discover drugs to counteract multidrug resistance in diseases such as cancer. In one comprehensive volume, this book contains a collection of the most current knowledge on the involvement of ABC transporters in drug transport and resistance. This comprehensive volume provides an overview on the description of the structure, the genome, normal tissue expression, physiological aspect, and mechanism of action of the ABC protein. The expert contributors explore the expression, detection, and implications of ABC proteins in hematological malignancies and solid tumors and ABC proteins and pathogenic microorganisms. This volume also explains MDR modulation through inhibition of ABC transporters and the design of inhibitors and mechanism of action. In addition, the book offers essential information on the biological and clinical aspect of multidrug resistance.

* Subject to ProQuest Ebook Centralï¿½ availability

Follow Matthews Book Co. on: