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Adenosine Receptors in Health and Disease

Wilson, Constance N.

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Book Information
Edition:	1st
Publisher:	Springer Nature
ISBN:	3-540-89615-5 (3540896155)
ISBN-13:	978-3-540-89615-9 (9783540896159)
Binding:	E E Book + ProQuest Ebook Central
Copyright:	2009
Publish Date:	09/09
Volume:	193
Weight:	0.00 Lbs.
Subject Class:	PRM (Pharmacology)
Return Policy:	Non-Returnable.
Table Of Contents:	View

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Class Specifications
ISSN Series:	Handbook of Experimental Pharmacology
Discipline:	Biochemistry
Subject Definition:	Receptors, Purinergic P1-Antagonists & Inhibitors
NLM Class:	QU 58
LC Class:	QP625
Abstract:	Since their discovery approximately 25 years ago, adenosine receptors have now emerged as important novel molecular targets in disease and drug discovery. These proteins play important roles in the entire spectrum of disease from inflammation to immune suppression. Because of their expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including asthma, rheumatoid arthritis, Parkinson's disease, multiple sclerosis, Alzheimer's disease, heart disease, stroke, cancer, sepsis, and obesity. As a result of intense investigations into understanding the molecular structures and pharmacology of these proteins, new molecules have been synthesized that have high specificity for these proteins and are now entering clinical trials. These molecules will define the next new classes of drugs for a number of diseases with unmet medical needs.

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