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Chromosome Translocation

Zhang, Y

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Book Information
Edition:	1st
Publisher:	Springer Nature
ISBN:	981-1305-93-5 (9811305935)
ISBN-13:	978-981-1305-93-1 (9789811305931)
Binding:	E E Book + ProQuest Ebook Central
Copyright:	2018
Publish Date:	08/18
Volume:	1044
Weight:	0.00 Lbs.
Subject Class:	GEN (Genetics)
Return Policy:	Non-Returnable.

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Class Specifications
ISSN Series:	Advances in Experimental Medicine & Biology
Discipline:	Biochemistry
Subject Definition:	Translocation, Genetic
NLM Class:	QU 477
LC Class:	QH462
Abstract:	This volume discusses various aspects of mechanisms and methodologies of chromosome translocations, ranging from a historical and clinical overview of chromosome translocations to the rapid development of the next-generation sequencing technologies, which has dramatically increased our understanding of the spectrum of chromosome translocations in human diseases.The book also introduces the mechanistic studies on chromosome deletions and their implications in cancer, and discusses the mechanisms of regulating chromothripsis, a unique complex type of chromosome translocation.It is a valuable resource for students and researchers alike, providing insights into chromosome translocations and, potentially, other genomic aberrations involved in understanding and curing human diseases.

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