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Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis. Consensus Study Report
NAP
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Book Information
Edition:
1st
Publisher:
National Academies Press
ISBN:
0-309-67211-2 (0309672112)
ISBN-13:
978-0-309-67211-5 (9780309672115)
Format:
Proceedings
Binding:
E E Book + ProQuest Ebook Central
Copyright:
2020
Publish Date:
04/20
Weight:
0.00 Lbs.
Subject Class:
PRM (Pharmacology)
Return Policy:
Non-Returnable.
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Class Specifications
Discipline:
Pharmacology
Subject Definition:
Antimalarials-Adverse Effects; Malaria; Military Health
NLM Class:
QV 256
LC Class:
RC158
Abstract:
Among the many who serve in the United States Armed Forces and who are deployed to distant locations around the world, myriad health threats are encountered. In addition to those associated with the disruption of their home life and potential for combat, they may face distinctive disease threats that are specific to the locations to which they are deployed. U.S. forces have been deployed many times over the years to areas in which malaria is endemic, including in parts of Afghanistan and Iraq. Department of Defense (DoD) policy requires that antimalarial drugs be issued and regimens adhered to for deployments to malaria-endemic areas. Policies directing which should be used as first and as second-line agents have evolved over time based on new data regarding adverse events or precautions for specific underlying health conditions, areas of deployment, and other operational factors. At the request of the Veterans Administration, Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis assesses the scientific evidence regarding the potential for long-term health effects resulting from the use of antimalarial drugs that were approved by FDA or used by U.S. service members for malaria prophylaxis, with a focus on mefloquine, tafenoquine, and other antimalarial drugs that have been used by DoD in the past 25 years. This report offers conclusions based on available evidence regarding associations of persistent or latent adverse events.
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