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Inflammatory Disorders

Pokorski, Mieczyslaw

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Book Information
Edition:	1st
Publisher:	Springer Nature
ISBN:	3-319-10012-2 (3319100122)
ISBN-13:	978-3-319-10012-8 (9783319100128)
Format:	Low Page Count
Binding:	E E Book + ProQuest Ebook Central
Copyright:	2015
Publish Date:	12/14
Volume:	839
Weight:	0.00 Lbs.
Subject Class:	R-M (Respiratory Medicine)
Return Policy:	Non-Returnable.
Table Of Contents:	View

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Class Specifications
ISSN Series:	Advances in Experimental Medicine & Biology
Discipline:	Pathology
Subject Definition:	Inflammation
NLM Class:	QZ 150
LC Class:	RB131
Abstract:	The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of action of common drugs used in COPD, such as formoterol, tiotropium, or corticosteroids, and point to novel drug targets. The chapters also deal with brain damaging effects, by far unrecognized, of inhaled corticosteroid therapy, a time-proven management of chronic inflammatory airway conditions; asthma being a case in point. Novel methods, likely less producing side effects, of macrolide antibiotics administration by inhalation are discussed, emphasizing not only bacteriostatic but also anti-inflammatory action.

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