Medicinal Chemistry of Anticancer Drugs

Avendano, Carmen

Other formats:

Book Information
Edition:	1st
Publisher:	Elsevier Science Publishing Company
ISBN:	0-444-52824-5 (0444528245)
ISBN-13:	978-0-444-52824-7 (9780444528247)
Binding:	Hardcover
Copyright:	2008
Publish Date:	06/08
Weight:	2.30 Lbs.
Pages:	442
Carton Quantity:	10
Subject Class:	ONC (Oncology)
Return Policy:	Returns accepted up to 90 days provided no other recalls or return restrictions apply.
Table Of Contents:	View
Contributing Authors:	View
ProQuest Ebook Central:	Available in ProQuest Ebook Central™ View

Class Specifications
Discipline:	Pathology
Subject Definition:	Antineoplastic Agents-Therapeutic Use; Neoplasms-Drug Ther
NLM Class:	QZ 267
LC Class:	RS431
Abstract:	Antitumour chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point of view of medicinal chemistry and drug design. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells. These therapies are in their infancy, but they hold promise of more effective therapies with fewer side effects. Resistance to antitumour drugs is another important but normally neglected field. The focus of Medicinal Chemistry of Anticancer Drugs is on the mechanism of action of antitumour drugs from the molecular point of view and on the relationship between chemical structure and chemical and biochemical reactivity of antitumour agents, aiming at the rationalization of the action of this type of drugs, which would allow the design of new active structures.