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ebc item NOTICE: This is the ProQuest Ebook Central� format of this title. What is ProQuest Ebook Central�?
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Samples Sizes for Clinical Trials

Julious, Steven A.
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Book Information
Edition: 1st
Publisher: Chapman & Hall
ISBN: 1-58488-740-0 (1584887400)
ISBN-13: 978-1-58488-740-9 (9781584887409)
Binding: E E Book + ProQuest Ebook Central
Copyright: 2010
Publish Date: 08/09
Weight: 0.00 Lbs.
Carton Quantity: 24
Subject Class: RET (Returns)
Remarks:
A New Edition of this Title is Available
Return Policy: Non-Returnable.
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Class Specifications
Discipline: Pharmacology
Subject Definition: Clinical Trials as Topic-Methods; Sample Size
NLM Class: QV 771
LC Class: R853
Abstract: Drawing on various real-world applications, Sample Sizes for Clinical Trials takes readers through the process of calculating sample sizes for many types of clinical trials. It provides descriptions of the calculations with a practical emphasis. Focusing on normal, binary, ordinal, and survival data, the book explores a range of trials, including superiority, equivalence, non-inferiority, bioequivalence, and precision for both parallel group and crossover designs. The author discusses how trial objectives impact the study design with respect to the derivation of formulae for sample size calculations. He uses real-life studies throughout to show how the concepts and calculations can be employed. This work underscores the importance of sample size calculation in the design of a clinical trial. With useful calculation tables throughout, it enables readers to quickly find an appropriate formula, formula application, and associated worked example.
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