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Cytokine Storm Syndrome
Cron, Randy Q.
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Book Information
Edition: 1st
Publisher: Springer Nature
ISBN: 3-030-22093-1 (3030220931)
ISBN-13: 978-3-030-22093-8 (9783030220938)
Format: Textbook
Binding: Hardcover
Copyright: 2019
Publish Date: 10/19
Weight: 2.34 Lbs.
Pages: 617
Subject Class: AIM (Allergy and Immunology)
Return Policy: Returns accepted up to 12 months provided no other recalls or return restrictions apply.
Contributing Authors: View
ProQuest Ebook Central: Also available in ProQuest Ebook Central Available in ProQuest Ebook Central™ View
 
Class Specifications
Discipline: Micro/Immuno
Subject Definition: Cytokines; Imuune System Diseases
NLM Class: QW 504
LC Class: RC582
Abstract: Cytokine Storm Syndromes, including HLH and MAS, are frequently fatal disorders, particularly if not recognized early and treated during presentation. The genetics of Cytokine Storm Syndromes are being defined with many of the risk alleles giving rise to mutations in the perforin-mediated cytolytic pathway used by CD8 cytotoxic T cells and natural killer cells. These are being studied using murine models. Up to 10% of the general population may carry risk alleles for developing Cytokine Storm Syndromes, and Cytokine Storm Syndromes are being increasingly recognized around the world in pediatric and adult hospitals.A variety of infectious, rheumatic, and oncologic triggers are commonly associated with Cytokine Storm Syndromes, but understanding this disorder is critical for all researchers and physicians to ensure timely and appropriate therapy. This textbook, the first of its kind, addresses all aspects of the disorder from genetics, pathophysiology, and ongoing research, to clinical presentations, risk factors, and treatment.
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