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Coenzyme B12 Enzymes, Part B

Marsh, Neil
Coenzyme B12 Enzymes, Part B Cover Image
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Book Information
Edition: 1st
Publisher: Academic Press, Incorporated
ISBN: 0-323-95557-6 (0323955576)
ISBN-13: 978-0-323-95557-7 (9780323955577)
Binding: Hardcover
Copyright: 2022
Publish Date: 06/20
Volume: 669
Weight: 1.66 Lbs.
Pages: 384
Subject Class: BCH (Biochemistry)
Return Policy: Returns accepted up to 90 days provided no other recalls or return restrictions apply.
Contributing Authors: View
 
Class Specifications
ISSN Series: Methods in Enzymology
Discipline: Biochemistry
Subject Definition: Vitamin B12; Enzymes
NLM Class: QU 194
LC Class: RC627
Abstract: Coenzyme B12 Enzymes, Part B, Volume 169 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on Structural characterization of cobalamin-dependent radical SAM methylases, Purification and characterization of sequential cobalamin-dependent radical SAM methylases ThnK and TokK in -lactam antibiotic biosynthesis, Characterization of the cobalamin-dependent radical S-adenosyl-L-methionine enzyme C-methyltransferase Fom3 in fosfomycin biosynthesis, Studies of OxsB and GenK, two B12-dependent radical SAM enzymes involved in natural product biosynthesis, Purification and structural elucidation of the cobalamin-dependent radical SAM enzyme OxsB, and more. Other chapters discuss Methods for studying the mechanisms of B12 enzymes, Computational investigations of B12 dependent enzymatic reactions, Using kinetic isotope effects to probe the mechanisms of adenosylcobalamin-dependent enzymes, Steady-state and pre-steady state kinetic analysis of ornithine 4,5-aminomutase, and more.

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