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ebc item NOTICE: This is the ProQuest Ebook Central� format of this title. What is ProQuest Ebook Central�?
Other formats: Hardcover All Formats

GAPDH: Biological Properties and Diversity

Seidler, Norbert W.
GAPDH: Biological Properties and Diversity Cover Image
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Book Information
Edition: 1st
Publisher: Springer Nature
ISBN: 94-007-4716-0 (9400747160)
ISBN-13: 978-94-007-4716-6 (9789400747166)
Binding: E E Book + ProQuest Ebook Central
Copyright: 2013
Publish Date: 08/12
Volume: 985
Weight: 0.00 Lbs.
Subject Class: BCH (Biochemistry)
Return Policy: Non-Returnable.
Table Of Contents: View
   
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Class Specifications
ISSN Series: Advances in Experimental Medicine & Biology
Discipline: Biochemistry
Subject Definition: Glyceraldehyde-3-Phosphate Dehydrogenases
NLM Class: QU 135
LC Class: QP601
Abstract: The book represents a comprehensive review and synthesis of the biomedical literature that spans over a half-century on a single protein called glyceraldehyde 3-phosphate dehydrogenase (or, GAPDH). Due to the protein's involvement in a vast array of cellular activities, GAPDH is of interest to the cell biologist, immunologist, virologist, biochemist etc. The protein has a significant role in fertility, cancer and neurodegeneration, suggesting that this book can be a vital resource for drug development. GAPDH function may provide insight into anesthesia. Furthermore, GAPDH is highly conserved meaning that the protein found in microorganisms, such as pathogens, remained relatively unchanged in evolution. Pathogens use GAPDH as a virulence factor, offering a unique challenge in developing anti-microbial agents that target this protein. To the evolutionary biologist, a book on the multi-functionality of GAPDH provides a focal point for a cogent discussion on the very origin of life.
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