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Available: 0 |
List Price:$239.25 |
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Other formats:
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Edition: | 1st |
Publisher: | Wiley-VCH |
ISBN: | 3-527-33904-3 (3527339043) |
ISBN-13: | 978-3-527-33904-4 (9783527339044) |
Binding: | Hardcover |
Copyright: | 2016 |
Publish Date: | 10/16 |
Volume: | 7 |
Weight: | 2.96 Lbs. |
Pages: | 576 |
Carton Quantity: | 8 |
Subject Class: | NEU (Neurology and Neuroscience) |
Remarks: | This Title is Out of Print |
Out Of Print: | Yes |
Return Policy: | Returns accepted up to 12 months provided no other recalls or return restrictions apply. |
ProQuest Ebook Central: |
Available in ProQuest Ebook Centralâ„¢ View
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Discipline: | Parasitology | Subject Definition: | Parasites-Metabolism; Research; Drug Discovery; Metabolomics | NLM Class: | QX 20 | LC Class: | RC119 | Abstract: | Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art omics technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented. |
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