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Genetics and Development of Scoliosis

Kusumi, K

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Book Information
Edition:	2nd
Publisher:	Springer Nature
ISBN:	3-319-90149-4 (3319901494)
ISBN-13:	978-3-319-90149-7 (9783319901497)
Binding:	E E Book + ProQuest Ebook Central
Publish Date:	06/18
Weight:	0.00 Lbs.
Subject Class:	GEN (Genetics)
Return Policy:	Non-Returnable.

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Class Specifications
Discipline:	Musculoskele
Subject Definition:	Scoliosis; Bone Dis-Genetics; Spine-Growth & Development
NLM Class:	WE 735
LC Class:	RD771
Abstract:	This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.

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