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Data Monitoring in Clinical Trials: A Case Studies Approach

DeMets, David L.
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Book Information
Edition: 1st
Publisher: Springer Nature
ISBN: 0-387-20330-3 (0387203303)
ISBN-13: 978-0-387-20330-0 (9780387203300)
Binding: Softcover
Copyright: 2006
Publish Date: 10/05
Weight: 1.26 Lbs.
Pages: 374
Subject Class: SCI (Medical Science and Research)
Remarks:
Print on Demand. Please allow additional time for delivery.
Return Policy: Returns accepted up to 12 months provided no other recalls or return restrictions apply.
Table Of Contents: View
Contributing Authors: View
 
Class Specifications
Discipline: Medical Prof
Subject Definition: Clinical Trials; Data Collection-Methods
NLM Class: W 20.5
LC Class: R853
Abstract: This book will be useful to anyone serving on a data and safety monitoring board, or planning to do so, for colleagues in academia, industry and governmental agencies, and for teaching students in biostatistics, epidemiology, clinical trials and medical ethics. No other text has as extensive a collection of cases which provide insight into the many issues, often conflicting, that must be examined before recommendations to continue or discontinue a trial can be made. While depth in statistical methods is not required, some familiarity with statistical design and analysis issues in clinical trials is helpful. The cases cover trials which were terminated early for convincing evidence of benefit, or for harmful effects. Cases with complex issues are also included. This series of cases should provide broad background information for potential monitoring committee members and better prepare them for the challenges that may exist in the trials for which they are responsible.

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