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| Available: 0 |
| List Price:$239.25 |
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| Edition: | 1st |
| Publisher: | Wiley-VCH |
| ISBN: | 3-527-33904-3 (3527339043) |
| ISBN-13: | 978-3-527-33904-4 (9783527339044) |
| Binding: | Hardcover |
| Copyright: | 2016 |
| Publish Date: | 10/16 |
| Volume: | 7 |
| Weight: | 2.96 Lbs. |
| Pages: | 576 |
| Carton Quantity: | 8 |
| Subject Class: | NEU (Neurology and Neuroscience) |
| Remarks: | This Title is Out of Print |
| Out Of Print: | Yes |
| Return Policy: | Returns accepted up to 12 months provided no other recalls or return restrictions apply. |
| ProQuest Ebook Central: |
Available in ProQuest Ebook Central™ View
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| Discipline: | Parasitology | | Subject Definition: | Parasites-Metabolism; Research; Drug Discovery; Metabolomics | | NLM Class: | QX 20 | | LC Class: | RC119 | | Abstract: | Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art omics technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented. |
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