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Drug Selectivity: An Evolving Concept in Medicinal Chemistry

Handler, N

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Book Information
Edition:	1st
Publisher:	Wiley, John & Sons, Inc.
ISBN:	3-527-67441-1 (3527674411)
ISBN-13:	978-3-527-67441-1 (9783527674411)
Binding:	E E Book + ProQuest Ebook Central
Copyright:	2018
Publish Date:	02/18
Volume:	72
Weight:	0.00 Lbs.
Subject Class:	PRM (Pharmacology)
Return Policy:	Non-Returnable.

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Class Specifications
ISSN Series:	Methods and Principles in Medicinal Chemistry
Discipline:	Pharmacology
Subject Definition:	Drug Design; Pharmaceutical Preparations-Chemistry
NLM Class:	QV 745
LC Class:	RM301.25
Abstract:	The book provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process. The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist.

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