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| Available: Yes* |
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| Edition: | 1st |
| Publisher: | Springer Nature |
| ISBN: | 981-1388-71-7 (9811388717) |
| ISBN-13: | 978-981-1388-71-2 (9789811388712) |
| Binding: | E E Book + ProQuest Ebook Central |
| Copyright: | 2019 |
| Publish Date: | 08/19 |
| Volume: | 1165 |
| Weight: | 0.00 Lbs. |
| Subject Class: | BIO (Biostatistics and Epidemiology) |
| Return Policy: | Non-Returnable. |
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| ISSN Series: | Advances in Experimental Medicine & Biology | | Discipline: | Urogenital Sys | | Subject Definition: | Kidney Diseases-Physiopathology; Fibrosis | | NLM Class: | WJ 300 | | LC Class: | RC903.9 | | Abstract: | This book systemically presents the latest research on renal fibrosis, covering all the major topics in the field, including the possible mechanisms, biomarkers, and strategies for prevention and treatment of chronic kidney disease (CKD). Due to its high prevalence, CKD represents a huge global economic and social burden. Irrespective of the initial causes, CKD progresses to end stage kidney disease (ESKD) due to renal fibrosis, which is characterized by glomerulosclerosis, tubule atrophy and atresia, and the excessive accumulation of extracellular matrix (ECM) in the kidney. Unfortunately, an estimated 1%-2% of the adult population living with CKD will need renal replacement therapy at some point as a result of ESKD. As such, strategies for preventing or slowing CKD progression to ESKD are of utmost importance, and studies aiming to understand the mechanisms of renal fibrosis have been the focus of intensive research. |
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