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Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery

Miller, S

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Available: Yes*
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Book Information
Edition:	1st
Publisher:	Wiley-Blackwell
ISBN:	3-527-69411-0 (3527694110)
ISBN-13:	978-3-527-69411-2 (9783527694112)
Binding:	E E Book + ProQuest Ebook Central
Copyright:	2016
Publish Date:	10/16
Volume:	7
Weight:	0.00 Lbs.
Carton Quantity:	8
Subject Class:	RET (Returns)
Return Policy:	Non-Returnable.

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Class Specifications
Discipline:	Parasitology
Subject Definition:	Parasites-Metabolism; Research; Drug Discovery; Metabolomics
NLM Class:	QX 20
LC Class:	RC119
Abstract:	Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art omics technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented.

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